Data-efficient learning and optimization methods form a central theme of a majority of our research activities. Such methods are particularly important in the context of (expensive) experiments/simulation-driven design and analysis of systems across domains as varied as electrical engineering, computational fluid dynamics and systems biology. Our research is therefore highly interdisciplinary and driven by real-world problems. Research challenges encountered in problems involving computationally expensive simulation models include – sampling or selection of simulation locations, training fast and accurate surrogate models of simulators which minimizing training dataset size, optimizing the simulator while minimizing the number of computationally expensive simulations, performing likelihood-free parameter inference from observed datasets, among others. The following themes provide an overview of our recent research activities.